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. 2021 Jul 12;9:700029. doi: 10.3389/fcell.2021.700029

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Copyright © 2021 Zhong, Luo, Fan, Wang, Liu, Xu and Zhang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effects of DGCR5 isoform-1 on RCC cell viability and migration by targeting miR-211-5p. (A,B) The CCK8 assay was carried out to detect the cell viability of A704 cells transfected with siRNA targeting DGCR5 (si664 or si523), miR-211-5p inhibitors or both siRNA and miR-211-5p inhibitors. (C,D) The transwell cell migration assay was carried out to test the migratory capability of A704 cells transfected with siRNA targeting DGCR5 (si664 or si523), miR-211-5p inhibitors or both siRNA and miR-211-5p inhibitors. All experiments were repeated in triplicate. Error bars stand for the mean ± SD; ^##P < 0.0001. miR-211-5p-i, microRNA-211-5p inhibitors.