Table 2.
|
Granin protein
|
Cleavage product
|
| CgA1 | Vasostatin-I (CgA1-76) and -II (CgA1-115) |
| Betagranin (CgA1-128) | |
| CgA10-19 and CgA43-521 | |
| Chromofungin (CgA47-66) | |
| Vasoconstriction-inhibiting factor (CgA79-113) | |
| Chromostatin (CgA124-143) | |
| Chromacin (CgA173-194) | |
| Pancreastatin (CgA250-301)1 | |
| WE-14 (CgA324-337)1 | |
| Cateslitin (CgA344-358) | |
| Catestatin (CgA352-372)1 | |
| Parastatin (CgA357-428) | |
| GE-25 (CgA367-391) | |
| Serpinin (CgA417-442) | |
| CgB1 | CgB1-41 |
| GAWK (CgB420-493) | |
| BAM-1745 (CgB579-593) | |
| PE-11 (CgB555-565) | |
| Secretolytin (CgB647-657) | |
| 43kDa large CgB fragment | |
| SgII1 | Secretoneurin (conjugate of SgII133-151 and SgII154-186) |
| EM66 (66 amino acid long) | |
| Manserin (SgII497-536) | |
| SgIII1 | –2 |
| HISL-19 | –2 |
| 7B2 | –2 |
| NESP55 | LSAL (NESP55159-162) |
| GAIPIRRH (NESP55234-241) | |
| VGF | Neuroendocrine regulatory peptide-1 (VGF281-306) |
| Neuroendocrine regulatory peptide-2 (VGF310-347) | |
| NAPP129 or VGF20 (VGF417-617) | |
| TPGH (VGF422-430) | |
| TLQP-21 (VGF556-576) | |
| TLQP-62 or VGF10 (VGF556-617) | |
| HHPD-41 (VGF576-617) | |
| AQEE-11 (VGF588-599) | |
| AQEE-30 (VGF588-617) | |
| LQEQ-19 (VGF599-617) | |
| proSAAS | KEP (proSAAS1-7) |
| Big SAAS (proSAAS1-26) | |
| Little SAAS (proSAAS9-26) | |
| GAV | |
| PEN (proSAAS188-209) | |
| PEN-LEN (proSAAS188-227) | |
| Little LEN (proSAAS212-221) | |
| Big LEN (proSAAS212-227) |
1
Granins and their cleavage products involved in carbohydrate metabolism.
2
No cleavage product described to date. CgA: Chromogranin A; CgB: Chromogranin B; NESP55: Neuroendocrine secretory protein with an apparent molecular weight of 55000 Daltons; SgII: Secretogranin II.