Table 6.

Hepatitis E virus highlights

	Hepatitis E virus
1	HEV is transmitted by the fecal-oral route (involving contaminated waters) and also as a zoonosis
2	In the last years, many studies have focused on HEV detection in environmental and food matrices, and blood products as alternative sources of infection
3	A new etiological agent of human hepatitis E, Orthohepevirus C, previously known to infect rats, has been recently described
4	Although most cases of HEV infection produce acute hepatitis, chronic infections seem to be an increasing problem, particularly in Europe
5	Complications and extrahepatic manifestations are also increasingly recognized
6	Only one vaccine for HEV has been licensed in China, with little known data, which limits its use

HEV: Hepatitis E virus.