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. 2021 Jul 12;15:695138. doi: 10.3389/fnins.2021.695138

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Copyright © 2021 Lohkamp, Kiliaan, Shenk, Verweij and Wiesmann.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) Representative images of retardance and dispersion maps of both running wheel (RW) and no running wheel mice (NRW) 1 week post-stroke, taken at the level of bregma 0.14, 0.5, and –1.94. (B) Retardance and (C) dispersion assessed with polarized light imaging (PLI) in the ipsilateral (R: right) contralateral (L: left) hemisphere of several ROI (AC: anterior commissure, CPD: cerebral peduncle, CC: corpus callosum, EC: external capsule, FI: fimbria, HI: hippocampus, IC: internal capsule, MC: motor cortex, OT: optic tract, SSC: somatosensory cortex, TH: thalamus). RW: N = 5, NRW: N = 4; values represented in mean ± SEM. ^#0.05 < p < 0.08 (tendency); *p ≤ 0.05; **p ≤ 0.01; ***p ≤ 0.001.