Table 2.
miRNAs That Are Validated to Target Differentially Regulated Genes in AA Women with Luminal A Breast Cancer From the Troester Group (D’Arcy et al., 2015)
| Gene Symbol | Gene Name | Up- or Downregulated in AA | Validated miRNAs | Intronic RNAs |
|---|---|---|---|---|
| SQLE | Squalene epoxidase | Up | 0 | |
| TYMS | Thymidylate synthetase | Up | Let-7b-5p miR-196a-5p miR-433-3p |
|
| ACOX2 | Acyl-CoA oxidase 2, branched chain | Down | miR-26b-5p | |
| MUC1 | Mucin 1, cell surface associated | Down | miR-145-5p miR-1226-3p miR-125b-5p miR-124-3p miR-455-3p |
Validated miRs are based on those annotated in miRTarBase 2016 with either one or more strong evidence and two or more less strong evidence (Chou et al., 2016).