Table 2.
SBI-R item means and association with depression and inflammation
| Mean (SD) | SBI-R Total |
PHQ-9 total |
HADS-D |
CRP |
|||||
|---|---|---|---|---|---|---|---|---|---|
| Range 0–3 | r | p | r | p | R | p | r | p | |
| SBI-R Total | - | - | 0.78 | <0.001 | 0.77 | <0.001 | 0.47 | <0.001 | |
| S1: Psychomotor retardation | 0.68 (0.87) | 0.57 | <0.001 | 0.46 | <0.001 | 0.51 | <0.001 | 0.19 | 0.07 |
| S2: Appetite | 0.81 (1.08) | 0.54 | <0.001 | 0.49 | <0.001 | 0.35 | 0.001 | 0.17 | 0.10 |
| S3: Pain severity | 0.98 (1.06) | 0.47 | <0.001 | 0.32 | <0.001 | 0.28 | 0.006 | 0.28 | 0.01 |
| S4: Decreased eating sweets | 0.44 (0.90) | 0.45 | <0.001 | 0.27 | <0.001 | 0.24 | 0.02 | −0.01 | 0.94 |
| S5: Libido | 0.60 (1.12) | 0.49 | <0.001 | 0.39 | <0.001 | 0.32 | 0.002 | 0.09 | 0.40 |
| S6: Fatigue | 1.40 (0.98) | 0.67 | <0.001 | 0.56 | <0.001 | 0.66 | <0.001 | 0.40 | <0.001 |
| S7: Motivated | 0.93 (0.98) | 0.82 | <0.001 | 0.65 | <0.001 | 0.66 | <0.001 | 0.33 | 0.001 |
| S8: Enjoyment of activities | 0.58 (0.86) | 0.62 | <0.001 | 0.51 | <0.001 | 0.56 | <0.001 | 0.38 | <0.001 |
| S9: Concentration | 0.44 (0.71) | 0.61 | <0.001 | 0.41 | <0.001 | 0.49 | <0.001 | 0.16 | 0.14 |
| S10: Sleep disturbance | 0.69 (0.87) | 0.42 | <0.001 | 0.40 | <0.001 | 0.38 | <0.001 | 0.12 | 0.26 |
| S11: Decreased socializing | 0.73 (0.93) | 0.71 | <0.001 | 0.54 | <0.001 | 0.33 | 0.002 | 0.23 | 0.03 |
| S12: Memory functioning | 0.40 (0.72) | 0.49 | <0.001 | 0.27 | 0.01 | 0.60 | <0.001 | 0.13 | 0.21 |
CRP, C-reactive protein; HADS-D, Hospital Anxiety and Depression Scale-Depression; PHQ-9, Patient Health Questionnaire; SBI-R, Sickness Behavior Inventory-Revised; SD, Standard Deviation.