Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Jul 12;11:685912. doi: 10.3389/fonc.2021.685912

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2021 Zhao, Bi, Lou, Yang and Sun

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Downregulation of SOX2-OT inhibited proliferation and invasion of HCC cells. SOX2-OT was intervened by siRNA (si-SOX2-OT#1, si-SOX2-OT#2, si-SOX2-OT#3) in HepG2 and Huh7 cells. The transfection of si-NC was used as control, and (A) the intervention effect of si-SOX2-OT was verified by RT-qPCR; the effects of si-SOX#2-OT2 with the best interference efficiency on cell proliferation, migration, and invasion were detected by (B) CCK-8 and (C) colony formation assay and (D) Transwell assays. Cell experiment was repeated three times independently and data were all metrological data. All data were shown as mean ± standard deviation. One-way ANOVA was used for data analysis, followed by Tukey’s test. ***P < 0.001.