Figure 4.

Downregulation of miR-143-3p could reverse the inhibitory effect of si-SOX2-OT on HCC. The miR-143-3p inhibitor was delivered into HepG2 cells with si-SOX2-OT#2, and the cells with si-NC+inhibitor-NC were used as controls. Then, (A) RT-qPCR was used to verify the intervention effect of miR-143-3p inhibitor; (B) CCK-8, (C) colony formation assay, and (D) Transwell assays were used to assess the proliferation, invasion, and migration of cells. The cell experiment was repeated three times independently and data were all metrological data. All data were shown as mean ± standard deviation. One-way ANOVA was used for data analysis, followed by Tukey’s test. *P < 0.05, ***P < 0.001.