Fig 4. Ad libitum HFD access reduces ethanol intake in unlimited access “free-choice” (UAE) model.
A) Time course of body mass changes by group during drinking period (n=15/group). Dark line indicates mean, shaded area with dots indicates standard error of the mean. HFD significantly reduces: B) ethanol g/kg/24hrs, C) g/ethanol consumed/24hrs, C1) cumulative ethanol intake, and D) ethanol preference. Lines indicate mean, error bars indicate standard error of the mean. * indicates significant differences between groups, as determined by mixed-effects model ANOVA or unpaired t-test (C1); p<0.05. P-values from mixed-effects ANOVA indicated to the right of each figure.