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. 2021 Jul 12;13:695732. doi: 10.3389/fnagi.2021.695732

TABLE 4.

Comparison for cognitive function among different grades of total MRI CSVD burden after propensity score matching.

Total MRI CSVD burden
p
0 (n = 67) 1 (n = 40) 2 (n = 41) 3 (n = 33) 4 (n = 22)
MMSEb 29 (27, 30) 29 (27, 29) 29 (26, 30) 27 (25, 30) 26 (22, 29) 0.048*
MoCAb 26 (24, 28) 25 (23, 27) 26 (23, 27) 25 (22, 28) 23 (19, 26) 0.004*
Memorya 0.25 (0.75) –0.09 (0.63) –0.18 (0.84) –0.21 (0.89) –0.28 (0.89) 0.009*
Executive functiona 0.19 (0.61) 0.07 (0.56) –0.13 (0.80) –0.25 (0.57) –0.54 (0.65) <0.001*
Speed and motor controla 0.15 (0.90) 0.08 (0.61) –0.18 (0.91) –0.27 (0.90) –0.53 (0.84) 0.006*

MRI, magnetic resonance imaging; CSVD, cerebral small vessel disease; MMSE, Mini-Mental State Examination; MoCA, Montreal Cognitive Assessment. aMean (standard deviation). bMedian (quartiles). *p < 0.05.