TABLE 4.
Total MRI CSVD burden |
p | |||||
0 (n = 67) | 1 (n = 40) | 2 (n = 41) | 3 (n = 33) | 4 (n = 22) | ||
MMSEb | 29 (27, 30) | 29 (27, 29) | 29 (26, 30) | 27 (25, 30) | 26 (22, 29) | 0.048* |
MoCAb | 26 (24, 28) | 25 (23, 27) | 26 (23, 27) | 25 (22, 28) | 23 (19, 26) | 0.004* |
Memorya | 0.25 (0.75) | –0.09 (0.63) | –0.18 (0.84) | –0.21 (0.89) | –0.28 (0.89) | 0.009* |
Executive functiona | 0.19 (0.61) | 0.07 (0.56) | –0.13 (0.80) | –0.25 (0.57) | –0.54 (0.65) | <0.001* |
Speed and motor controla | 0.15 (0.90) | 0.08 (0.61) | –0.18 (0.91) | –0.27 (0.90) | –0.53 (0.84) | 0.006* |
MRI, magnetic resonance imaging; CSVD, cerebral small vessel disease; MMSE, Mini-Mental State Examination; MoCA, Montreal Cognitive Assessment. aMean (standard deviation). bMedian (quartiles). *p < 0.05.