Table 2.

Patient-reported respiratory outcome tools used in studies of patients diagnosed with EDS and HSD.

Tools	Domains	Population	Items/scoring	Minimally importance difference	Recall
Medical Research Council (MRC) Dyspnoea Scale 20	Dyspnea	EDS 7	5 items. Spectrum of respiratory disability from none (Grade 1) to almost complete incapacity (Grade 5).	Change 1 unit	Everyday activities
Borg Rating of Perceived Exertion Scale 21	Physical Activity Intensity Level	EDS/HSD 22,23	15-point scale (minimum 6 – maximum 20) from “not at all” to “very, very hard” exhausted Some studies use modified 10-Borg Dyspnea Scale	Change of 1–2 units in patients undergoing pulmonary rehabilitation or exercise intervention 24	Current
St George’s Respiratory Questionnaire 25	Chronic Airflow Limitation Symptoms, activity impacts	EDS/ HSD 9	50 items. Scores span from 0 to 100, with higher scores indicating more limitations.	A mean change score of 4 units is associated with slightly efficacious treatment, 8 units for moderately efficacious change and 12 units for very efficacious treatment in patients with asthma 26	3–12 months recall
Subjective health complaints inventory (SHC-I) 27	Somatic and mental health complaints 5 subscales, including: Allergic complaints (asthma, allergies, breathing difficulties, chest pain, and eczema) Colds subscale (colds, flu, coughs, and bronchitis)	EDS 28	The self-rated levels of affect are graded on a four-point Likert scale: 0 = not bothered, 1 = slightly bothered, 2 = partly bothered, and 3 = severely bothered. The 29 individual complaints are commonly reported on a total score (SHC-total), but can also be grouped into five subscales		Past 30 days
Epworth Sleepiness Scale 20	Subjective degree of daytime sleepiness	EDS 30,31	8 Items. Self-administered questionnaire where respondents rate chance of dozing off on a 4-point scale (0–3). Higher scores indicate more sleepiness (minimum 0 to maximum 24).	Change of 2 to 3 units. 32	Everyday sleep patterns