Table 1.

In silico analysis of the selected complex I genes and alternative dehydrogenase NDH2 encoded by nuclear DNA

Species	Homo sapiens	Trypanosoma brucei	Blechomonas ayalai	Leptomonas seymouri	Novymonas esmeraldas	Wallacemonas raviniae
Membrane domain	NDUFB1	Tb927.11.7390	Baya_011_0530	Lsey_0055_0260	+	+
	NDUFB7	Tb927.9.11660	Baya_100_0220	Lsey_0192_0100	+	+
	NDUFB9	Tb927.11.15810	Baya_019_0320	Lsey_0010_0080	+	+
	NDUFB10	Tb927.11.9930	Baya_039_0260	Lsey_0091_0010	+	+ (2)
	NDUFB11	Tb927.4.440	Baya_165_0080	Lsey_0525_0020	+	+
	NDUFAB1	Tb927.3.860	Baya_111_0040	Lsey_0115_0040	+	+
	NDUFS5	Tb927.3.5340	Baya_092_0110	Lsey_0041_0050	+	+
	NDUFA6	Tb927.10.14860	Baya_244_0010	Lsey_0011_0010	+	+
	NDUFA8	Tb927.10.12930	Baya_093_0130	Lsey_0013_0050	+	+ (3)
	NDUFA9	Tb927.10.13620	Baya_084_0070	Lsey_0157_0100	+	+
Peripheral domain	NDUFA13	Tb927.11.8910	Baya_029_0060	Lsey_0071_0190	+	+
	NDUFA12	Tb927.9.12680	Baya_004_0460	Lsey_0186_0050	+	+ (2)
	NDUFA5	Tb927.10.4130	Baya_191_0090	Lsey_0122_0100	+	+
	NDUFA2	Tb927.11.16870	Baya_038_0390	Lsey_0241_0060	+	+
	NDUFS7	Tb927.11.1320	Baya_018_0020	Lsey_0065_0230	+	+
	NDUFS6	Tb927.6.4270	Baya_060_0270	Lsey_0209_0010	+	+
	NDUFS1	Tb927.10.12540	Baya_080_0190	Lsey_0113_0150	+	+
	NDUFV2	Tb927.7.6350	Baya_155_0060	Lsey_0197_0040	+	+
	NDUFV1	Tb927.5.450	Baya_008_1080	Lsey_0248_0020	+	+
NDH2	–	Tb927.10.9440	Baya_062_0020	Lsey_0004_0940	+	+

All selected genes were detected in all analysed trypanosomatid genomes. The table lists either the names of genes in the TriTrypDB that was used for T. brucei, B. ayalai and L. seymouri or the ‘+’ sign indicating the presence in unannotated databases for N. esmeraldas and W. raviniae. All genes were found in one copy, except for a few genes of W. raviniae, for which a higher copy number is given in parentheses. Names of H. sapiens orthologues are also provided.