Table 1:

Comparison of CMD and Reference Subjects

Characteristic	CMD Subjects (n=36)	Reference Subjects (n=16)	p-Value
Age	57± 10	51± 20	0.8
Body Mass Index	27± 6	26 ± 4	0.7
Systolic Blood Pressure (mmHg)	118 ± 15	122 ± 16	0.3
Diastolic Blood Pressure (mmHg)	62 ± 8	68 ± 8	0.02
Heart Rate (bpm)	68 ± 12	65 ± 12	0.5
Hypertension	13 (36%)	0 (0%)	0.005
Diabetes Mellitus	4 (11%)	0 (0%)	0.3
Hyperlipidemia	14 (39%)	0 (0%)	0.002
Prior Tobacco Use	9 (25%)	0 (0%)	0.04
Statin	24 (67%)	0 (0%)	<0.001
Angiotensin Converting Enzyme Inhibitor (ACE-I)	9 (25%)	0 (0%)	0.05
Angiotensin Receptor Blocker	5 (14%)	0 (0%)	0.3
Aspirin	27 (75%)	1 (7%)	<0.001
Beta Blocker	15 (42%)	0 (0%)	0.004
Calcium Channel Blocker	10 (28%)	0 (0%)	0.05
Nitrate	21 (58%)	0 (0%)	<0.001
Ranolazine	8 (22%)	0 (0%)	0.2
Hormone Therapy	8 (22%)	3 (19%)	>0.9
Ambulatory Ischemia*	14 (39%)	0 (0%)	0.002
Silent Ischemia^	13 (36%)	0 (0%)	0.005

^*Defined as evidence of ≥ 1 minute horizontal or downsloping ST segment depression ≥ 1.0 mm, measured 80 ms from the J point on ambulatory monitoring; CMD = coronary microvascular dysfunction

^{^}Among those with ambulatory ischemia, the absence of chest pain or chest pain equivalents.