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Anti-CD14 antibody treatment improved vital signs following a lethal dose of Escherichia coli. A, Heart rate, (B) mean systemic arterial pressure (MSAP), (C) respiration, (D) oxygen saturation, and (E) core temperature. Data are presented as mean ± standard error of the mean. Same time points are compared between LD100 (red) and LD100 + anti-CD14 using multiple t-tests with Holm-Sidak correction for multiple comparisons. *P < .05, **P < .01, ****P < .0001
