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. 2021 Jul 21;16:2165–2179. doi: 10.2147/COPD.S305380

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© 2021 Winter et al.

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Relative mRNA abundance of (A) TPSB2, (B) CPA3, (C) KIT, (D) GATA2, (E) SOCS2, (F) ENO2, (G) GPR56, (H) HDC, and (I) combinatorial gene metric in COPD participants classified by frequent (>2) and infrequent (0–1) exacerbator status for total (frequent [n=58] and infrequent [n=38]) or severe (frequent [n=14] and infrequent [n=81]) exacerbations. Bars represent median, with error bars representing Q₁, Q₃. Relative mRNA abundance compared between groups are expressed as 2^−ΔCt relative to the housekeeping gene β-actin. Combinatorial gene metric based on ΔCt gene expression values. *p≤0.05.