Table 2. Effects of SBP trajectory on the risk of dementia.
Variables | Model 1 | Model 2 | Model 3 | Model 4 |
Normal SBP as reference | ||||
Stabilized SBP | 1.74(1.38, 2.20) *** | 1.75(1.38, 2.22) *** | 1.79(1.41, 2.27) *** | 1.62(1.27, 2.07) *** |
Elevated SBP | 0.64(0.46, 0.88) ** | 0.70(0.51, 0.96) * | 0.70(0.51, 0.96) * | 0.73(0.53, 1.00) |
Persistently high SBP | 0.96(0.61, 1.51) | 1.03(0.65, 1.62) | 1.03(0.65, 1.62) | 1.06(0.66, 1.69) |
Persistently high SBP as reference | ||||
Stabilized SBP | 1.82(1.10, 3.00) * | 1.71(1.03, 2.83) * | 1.74(1.05, 2.88) * | 1.53(0.91, 2.56) |
Elevated SBP | 0.67(0.39, 1.15) | 0.68(0.39, 1.18) | 0.68(0.39, 1.17) | 0.69(0.40, 1.20) |
Elevated SBP as reference | ||||
Normal SBP | 1.57(1.14, 2.15) ** | 1.43(1.04, 1.97) * | 1.44(1.05, 1.97) * | 1.38(1.00, 1.90) |
Stabilized SBP | 2.73(1.86, 4.01) *** | 2.51(1.71, 3.69) *** | 2.57(1.75, 3.77) *** | 2.22(1.51, 3.28) *** |
SBP, systolic blood pressure. Hazard ratios (95% confidence intervals) are presented. Model 1 was adjusted for no covariates. Model 2 was adjusted for age, gender, ethnic group, education, primary occupation before retirement, average household income, and place of residence. Model 3 was adjusted for model 2 plus smoking, alcohol use, regular exercise, sleep quality, sleep duration, and living alone. Model 4 was adjusted for model 3 plus heart rate, body mass index, hypertension, diabetes, heart disease, cerebrovascular disease, respiratory disease, and cancer. * P <0.05, **P < 0.01, *** P < 0.001.