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. 2021 Jul 1;13(13):17380–17406. doi: 10.18632/aging.203228

Table 2. Effects of SBP trajectory on the risk of dementia.

Variables Model 1 Model 2 Model 3 Model 4
Normal SBP as reference
Stabilized SBP 1.74(1.38, 2.20) *** 1.75(1.38, 2.22) *** 1.79(1.41, 2.27) *** 1.62(1.27, 2.07) ***
Elevated SBP 0.64(0.46, 0.88) ** 0.70(0.51, 0.96) * 0.70(0.51, 0.96) * 0.73(0.53, 1.00)
Persistently high SBP 0.96(0.61, 1.51) 1.03(0.65, 1.62) 1.03(0.65, 1.62) 1.06(0.66, 1.69)
Persistently high SBP as reference
Stabilized SBP 1.82(1.10, 3.00) * 1.71(1.03, 2.83) * 1.74(1.05, 2.88) * 1.53(0.91, 2.56)
Elevated SBP 0.67(0.39, 1.15) 0.68(0.39, 1.18) 0.68(0.39, 1.17) 0.69(0.40, 1.20)
Elevated SBP as reference
Normal SBP 1.57(1.14, 2.15) ** 1.43(1.04, 1.97) * 1.44(1.05, 1.97) * 1.38(1.00, 1.90)
Stabilized SBP 2.73(1.86, 4.01) *** 2.51(1.71, 3.69) *** 2.57(1.75, 3.77) *** 2.22(1.51, 3.28) ***

SBP, systolic blood pressure. Hazard ratios (95% confidence intervals) are presented. Model 1 was adjusted for no covariates. Model 2 was adjusted for age, gender, ethnic group, education, primary occupation before retirement, average household income, and place of residence. Model 3 was adjusted for model 2 plus smoking, alcohol use, regular exercise, sleep quality, sleep duration, and living alone. Model 4 was adjusted for model 3 plus heart rate, body mass index, hypertension, diabetes, heart disease, cerebrovascular disease, respiratory disease, and cancer. * P <0.05, **P < 0.01, *** P < 0.001.