Table 1. Baseline demographics and genetic characteristics of the study participants.
| Variables | Total patients (n = 299) | AD patients (n = 255) | MCI patients (n = 44) |
| Age (years) | 78.4 ± 7.0 | 79.3 ± 6.5 | 73.3 ± 7.7 |
| Sex (women) | 155 (51.8) | 134 (52.6) | 21 (47.7) |
| Education (years) | 9.5 ± 4.6 | 9.2 ± 4.6 | 11.5 ± 4.3 |
| MMSE (scores) | 20.0 ± 4.9 | 19.2 ± 4.7 | 24.7 ± 3.0 |
| APOE genotypes | |||
| ε2ε2/ε2ε3/ε3ε3 | 195 (65.2) | 166 (65.1) | 29 (65.9) |
| ε2ε4/ε3ε4 | 93 (31.1) | 81 (31.8) | 12 (27.3) |
| ε4ε4 | 11 (3.7) | 8 (3.1) | 3 (6.8) |
| ABCA7 rs3764650 | |||
| TT | 135 (45.2) | 111 (43.5) | 24 (54.6) |
| TG | 128 (42.8) | 113 (44.3) | 15 (34.1) |
| GG | 36 (12.0) | 31 (12.2) | 5 (11.4) |
| SORL1 rs3737529 | |||
| CC | 183 (61.2) | 150 (58.8) | 33 (75.0) |
| CT | 99 (33.1) | 90 (35.3) | 9 (20.5) |
| TT | 17 (5.7) | 15 (5.9) | 2 (4.6) |
| SORL1 rs1784933 | |||
| AA | 139 (46.5) | 114 (44.7) | 25 (56.8) |
| AG | 134 (44.8) | 118 (46.3) | 16 (36.4) |
| GG | 26 (8.7) | 23 (9.0) | 3 (6.8) |
| SORL1 rs2298813 | |||
| GG | 251 (84.0) | 215 (84.3) | 36 (81.8) |
| GA | 45 (15.1) | 38 (14.9) | 7 (15.9) |
| AA | 3 (1.0) | 2 (0.8) | 1 (2.3) |
| BIN1 rs744373 | |||
| AA | 104 (34.8) | 90 (35.3) | 14 (31.8) |
| AG | 142 (47.5) | 117 (45.9) | 25 (56.8) |
| GG | 53 (17.7) | 48 (18.8) | 5 (11.4) |
| GAB2 rs2373115 | |||
| CC | 139 (46.5) | 125 (49.0) | 14 (31.8) |
| CA | 120 (40.1) | 97 (38.0) | 23 (52.3) |
| AA | 40 (13.4) | 33 (12.9) | 7 (15.9) |
| CD33 rs3865444 | |||
| CC | 203 (67.9) | 173 (67.8) | 30 (68.2) |
| CA | 82 (27.4) | 71 (27.8) | 11 (25.0) |
| AA | 14 (4.7) | 11 (4.3) | 3 (6.8) |
The data are expressed as the mean ± SD or n (%).
Abbreviations: AD, Alzheimer’s disease; MCI, mild cognitive impairment; MMSE, Mini-Mental State Examination; APOE, apolipoprotein E.