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. 2021 May 17;13(13):17137–17154. doi: 10.18632/aging.203032

Table 1. Baseline participant characteristics.

Parameters Normal to high responders Poor responders P Effect size
E2 level on hCG day 3090.00(2295.00-4539.00) 1422.20(799.80-2267.80) <0.001 r = 0.396
follicle number on hCG day 12.00(8.00-16.25) 5.00(3.00-8.00) <0.001 r = 0.402
AFC 16.00(11.00-21.00) 9.00(5.00-13.00) <0.001 r = 0.365
AMH 3.09(1.99-5.05) 1.03(0.56-1.75) <0.001 r = 0.420
infertility duration 3.00(2.00-6.00) 4.00(2.00-6.00) 0.297 r = -0.031
infertility cause pelvic and fallopian tube factors 347(36.60) 51(31.48) <0.001 V = 0.211
ovulatory obstacle 74(7.81) 1(0.62)
endometriosis and uterine factors 42(4.43) 19(11.73)
decreased ovarian reserve 147(15.50) 32(19.75)
unexplained infertility 64(6.75) 22(19.75)
male factor 175(18.46) 20(12.35)
multiple confounding factors 99(10.44) 17(10.49)
therapeutic regimen long protocol 430(45.36) 51(31.48) <0.001 V = 0.268
super-long protocol 263(27.74) 21(12.96)
antagonist regimen 162(17.09) 34(20.99)
PPOS 87(9.18) 54(33.33)
others 6(0.63) 2(1.23)
age 30.0(28.0-33.0) 32.00(29.00-36.00) <0.001 r = -0.146
E2 35.60(31.45-41.99) 49.31(37.03-55.77) <0.001 r = -0.303
FSH 6.870(5.707-8.210) 8.315(6.798-10.515) <0.001 r = -0.217
LH 3.645(2.730-4.832) 3.515(2.525-4.562) 0.125 r = 0.046
days of Gn 10.00(9.00-11.00) 10.000(8.000-11.000) <0.001 r = 0.116
dosages of Gn 2250(1725-2900) 2700(2025-3200) <0.001 r = -0.117
pelvic surgery No 718(75.74) 120(74.07) 0.649 r = 0
Yes 230(24.26) 42(25.93)
gravidity history 0 484(51.05) 77(47.53) 0.522 r = 0
1 236(24.89) 41(25.31)
2 116(12.24) 21(12.96)
≥3 112(11.82) 23(14.19)
height 160.0(158.0-163.0) 160.0(158.0-163.0) 0.904 r = 0.004
weight 56.00(51.00-62.00) 56.00(51.00-64.00) 0.525 r = -0.019
BMI 21.64(19.98-23.93) 21.95(20.20-24.23) 0.357 r = -0.028
infertility type primary infertility 452(47.68) 72(44.44) 0.446 r = 0
secondary infertility 496(52.32) 90(55.56)

Normally distributed data, skewed distribution data and nominal data are described by mean ± SD, median ± interquartile range and frequency (relative frequency) respectively. Wilxon signed-rank test and chi-square test were applied in skew distribution data and nominal data respectively, and properly used r and V as the effect size to quantify the significance.