Table 1. Baseline participant characteristics.
Parameters | Normal to high responders | Poor responders | P | Effect size | |
E2 level on hCG day | 3090.00(2295.00-4539.00) | 1422.20(799.80-2267.80) | <0.001 | r = 0.396 | |
follicle number on hCG day | 12.00(8.00-16.25) | 5.00(3.00-8.00) | <0.001 | r = 0.402 | |
AFC | 16.00(11.00-21.00) | 9.00(5.00-13.00) | <0.001 | r = 0.365 | |
AMH | 3.09(1.99-5.05) | 1.03(0.56-1.75) | <0.001 | r = 0.420 | |
infertility duration | 3.00(2.00-6.00) | 4.00(2.00-6.00) | 0.297 | r = -0.031 | |
infertility cause | pelvic and fallopian tube factors | 347(36.60) | 51(31.48) | <0.001 | V = 0.211 |
ovulatory obstacle | 74(7.81) | 1(0.62) | |||
endometriosis and uterine factors | 42(4.43) | 19(11.73) | |||
decreased ovarian reserve | 147(15.50) | 32(19.75) | |||
unexplained infertility | 64(6.75) | 22(19.75) | |||
male factor | 175(18.46) | 20(12.35) | |||
multiple confounding factors | 99(10.44) | 17(10.49) | |||
therapeutic regimen | long protocol | 430(45.36) | 51(31.48) | <0.001 | V = 0.268 |
super-long protocol | 263(27.74) | 21(12.96) | |||
antagonist regimen | 162(17.09) | 34(20.99) | |||
PPOS | 87(9.18) | 54(33.33) | |||
others | 6(0.63) | 2(1.23) | |||
age | 30.0(28.0-33.0) | 32.00(29.00-36.00) | <0.001 | r = -0.146 | |
E2 | 35.60(31.45-41.99) | 49.31(37.03-55.77) | <0.001 | r = -0.303 | |
FSH | 6.870(5.707-8.210) | 8.315(6.798-10.515) | <0.001 | r = -0.217 | |
LH | 3.645(2.730-4.832) | 3.515(2.525-4.562) | 0.125 | r = 0.046 | |
days of Gn | 10.00(9.00-11.00) | 10.000(8.000-11.000) | <0.001 | r = 0.116 | |
dosages of Gn | 2250(1725-2900) | 2700(2025-3200) | <0.001 | r = -0.117 | |
pelvic surgery | No | 718(75.74) | 120(74.07) | 0.649 | r = 0 |
Yes | 230(24.26) | 42(25.93) | |||
gravidity history | 0 | 484(51.05) | 77(47.53) | 0.522 | r = 0 |
1 | 236(24.89) | 41(25.31) | |||
2 | 116(12.24) | 21(12.96) | |||
≥3 | 112(11.82) | 23(14.19) | |||
height | 160.0(158.0-163.0) | 160.0(158.0-163.0) | 0.904 | r = 0.004 | |
weight | 56.00(51.00-62.00) | 56.00(51.00-64.00) | 0.525 | r = -0.019 | |
BMI | 21.64(19.98-23.93) | 21.95(20.20-24.23) | 0.357 | r = -0.028 | |
infertility type | primary infertility | 452(47.68) | 72(44.44) | 0.446 | r = 0 |
secondary infertility | 496(52.32) | 90(55.56) |
Normally distributed data, skewed distribution data and nominal data are described by mean ± SD, median ± interquartile range and frequency (relative frequency) respectively. Wilxon signed-rank test and chi-square test were applied in skew distribution data and nominal data respectively, and properly used r and V as the effect size to quantify the significance.