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. Author manuscript; available in PMC: 2022 Feb 1.
Published in final edited form as: Epilepsia. 2020 Dec 17;62(2):481–491. doi: 10.1111/epi.16792

Figure 4. Anti-seizure medications demonstrate differences in IED rate reductions.

Figure 4.

(A) There was a significant reduction in the predicted IED rate for subjects on older generation (p < 0.001) and combined generation ASM regimens (p < 0.001) relative to the group taking no ASMs. (B) Our linear mixed-effects models revealed that seven of the ASMs were associated with significant overall IED rate reductions when referenced to the group taking no ASMs. Colors reflect significance values with a false discovery rate controlled at a level of 0.05. Bars represent 95% confidence intervals. * denotes older generation ASMs. “n” corresponds to the number of unique subject sessions contributing to each stratum. ASMs excluded due to a small number in our dataset were: Gabapentin, Divalproex sodium, Perampanel, Felbamate, Rufinamide, Primidone, and ASMs categorized as Other.