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. Author manuscript; available in PMC: 2021 Jul 26.
Published in final edited form as: Mol Cancer Ther. 2010 Dec;9(12):3289–3301. doi: 10.1158/1535-7163.MCT-10-0562

Figure 3.

Figure 3.

Cell cycle anlysis in cell lines with wt TP53 and mt TP53. SK-N-RA (wt TP53) and CHLA-90 (mt TP53) cells were pre-treated with 2 μM vorinostat (Vorin) for 24 hrs, and then 0.2 μM flavopiridol (F) was added for an additional 2, 4, 6, 8, 10, 12, 16, 18, or 24 hrs. G1, S, and G2/M phases of the cell cycle were then measured for permeabilized cells stained with propidium iodide using flow cytometry. Frequencies of intact cells in G1, S, and G2/M phases are given in the upper right of each histogram. Frequencies of sub-G1 events, indicative of dead cells, is shown on the left of each histogram.