Table 1.

Symptoms and examination findings

Pt	Sex	Age	Eye	Previous or current medication	PPVAL	ONSS	Brain MRI	History of migraine	Previous diagnosis	Quality of pain	Time course of pain	BCVA in affected eye on presentation	Final BCVA	Ishihara test presentation – final visit	RAPD	Therapy	Improvement with cycloplegic drops
1	F	18	OD	None	Yes	None	Normal	No	Retrobulbar ON	Throbbing	6–8 hours per day, 2–4 days per week	6/18	6/6	5/12 – 12/12	No	amitriptyline	Not given
2	M	25	OD	None	Yes	Nausea	Normal	Yes	Retrobulbar ON	Throbbing	12 hours, 1–2 days per week	6/36	6/6	2/12 – 12/12	No	amitriptyline	Not given
3	F	19	OS	NSAIDs	Yes	Malaise and headache	Normal	No	Retrobulbar ON	Throbbing	1–2 hours, 1 day per week	6/9	6/6	5/12 – 12/12	No	NSAIDs	Yes
4	F	45	OD	NSAIDs	Yes	None	Normal	NO	Retrobulbar ON	Sharp	Constant, 2–5 days per week	CF	6/6	TP – 12/12	No	NSAIDs	Yes

BCVA = Best corrected visual acuity; MRI = Magnetic resonance imaging; NSAIDs = Non-steroidal anti-inflammatory drugs, OD = Right eye; ON = Optic neuritis; ONSS = Other neurological or systemic symptoms; OS = Left eye; PPVAL = Photophobia, pain and visual acuity loss; Pt = Patient; RAPD = relative afferent pupil defect; TP = Test plate.