TABLE 4.
MIC (μg/ml) |
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Antibiotic | WT | ΔabaI | ΔabaR | ΔabaIR | ΔabaI(pMEabaI) | ΔabaR(pMEabaR) | WT(pME6032) | WT(pMEabaI) | WT(pMEabaR) |
Kanamycin | 8 | 2 | 4 | 4 | 4 | 8 | 8 | 8 | 16 |
Gentamicin | 4 | 1 | 4 | 0.25 | 2 | 4 | 4 | 4 | 4 |
Penicillin | 128 | 64 | 64 | 32 | 64 | 64 | 64 | 64 | 128 |
Streptomycin | 32 | 16 | 16 | 16 | 32 | 32 | 32 | 32 | 64 |
Meropenem | 1 | 0.25 | 0.5 | 0.25 | 0.5 | 0.5 | 1 | 1 | 1 |
Imipenem | 32 | 16 | 16 | 8 | 16 | 16 | 16 | 16 | 32 |
Ceftizoxime | 8 | 8 | 8 | 8 | 8 | 8 | 8 | 8 | 16 |
Cefepime | 2 | 8 | 8 | 2 | 8 | 8 | 8 | 8 | 8 |
Cefoperazone–sulbactam | 2 | 8 | 2 | 2 | 8 | 4 | 2 | 4 | 4 |
Piperacillin–tazobactam | 8 | 8 | 8 | 32 | 8 | 8 | 8 | 8 | 16 |
Vancomycin | >512 | >512 | 128 | >512 | >512 | >512 | >512 | >512 | >512 |
Ampicillin | 64 | 32 | 64 | 32 | 32 | 32 | 32 | 32 | 64 |
Tetracycline | 2 | 8 | 2 | 2 | 8 | 4 | 4 | 4 | 4 |
Spectinomycin | 64 | 64 | 64 | 64 | 64 | 64 | 64 | 64 | 64 |