TABLE I.
Study Summary Characteristics
| Study | LOE -Study Type* | No. of Participants | Age† (yr) | % Female | Duration of Follow-up† (mo) | Allograft‡ | Autograft‡ | ||||
| No. | No. Failed | % Failed | No. | No. Failed | % Failed | ||||||
| Razi26 (2019) | II - PC | 31 | 14.8 (ND) | 32% | 24 (ND) | 13 | 0 | 0% | 18 (HS) | 0 | 0% |
| Salem31 (2019) | III - CS | 256 | 18.4 (15-25) | 100% | 43 (30-64) | 18 (hybrid autograft/allograft) | 4 | 22% | 175 (BTB), 63 (HS) | 12 (BTB), 7 (HS) | 7% (BTB), 11% (HS) |
| Salmon32 (2018) | III - CC | 39 | 16 (14-18) | 67% | ND (≥240) | 0 | 0 | NA | 39 (HS) | 15 (HS) | 38% (HS) |
| Webster33 (2016) | III - RC | 316 | 17.2 (11-19) | 37% | 60 (36-120) | 0 | 0 | NA | 316 (HS) | 57 (HS) | 18% (HS) |
| Thompson34 (2016) | II - PC | 29 | ND (13-18) | ND | 240 (ND) | 0 | 0 | NA | 14 (BTB), 15 (HS) | 7§ | 24% |
| Engelman35 (2014) | III - CC | 73 | 15.4 (11-18) | 45% | 41.3 (ND) | 38 | 11 | 29% | 35 (HS) | 4 (HS) | 11% |
| Webster36 (2014) | III - CC | 110 | ND (<20) | ND | 57.6 (≥36) | 0 | 0 | NA | 110 (HS) | 15 (HS) | 14% |
| Mascarenhas37 (2012) | III - CC | 46 | 18 (ND) | 57% | 54 (24-120) | 0 | 0 | NA | 23 (BTB), 23 (HS) | 0 | 0% |
| Ellis et al.21 (2012) | III - RC | 79 | 16 (14-18) | 62% | 50.4 (24-135.6) | 20 | 7 | 35% | 59 (BTB) | 2 (BTB) | 3% |
| Pallis38 (2012) | II - PC | 120 (122 knees) | 19 (18-25) | 25% | ND (24-48) | 16 | 7 | 44% | 61 (BTB), 45 (HS) | 7 (BTB), 6 (HS) | 11% (BTB), 13% (HS) |
| Koizumi27 (2013) | III - RC | 15 | 14 (13-16) | 47% | 38# (25-48) | 0 | 0 | NA | 15 (HS) | 2 (HS) | 13% (HS) |
| Barrett28 (2011) | III - RC | 224 | 17.8 (12-25) | ND | ND (≥24) | 24 | 7 | 29% | 152 (BTB), 48 (HS) | 18 (BTB), 12 (HS) | 12% (BTB), 25% (HS) |
| Shelbourne29 (2009) | II - PC | 528** | ND (14-18) | 50% | ND (≥60) | 0 | 0 | NA | 528 (BTB) | 46 (BTB) | 9% (BTB) |
| Sankar30 (2006) | III - RC | 12 | 15.6 (14-17) | 50% | 64 (30-97) | 12 | 0 | 0% | 0 | 0 | NA |
*
LOE = level of evidence, PC = prospective cohort, CS = case series, CC = case-control, and RC = retrospective cohort.
†
The values are given as the mean, with the range in parentheses, unless otherwise specified. ND = no data.
‡
NA = not applicable, BTB = bone-patellar tendon-bone, and HS = hamstring.
§
No data on graft type.
#
Median.
**
Patients ≤18 years of age.