. 2021 Jul 26;95(16):e02401-20. doi: 10.1128/JVI.02401-20

TABLE 4.

IC₅₀ of ETV-TP and estimated K_m and V_max with dGTP for HIV RT

Enzyme	IC₅₀		V_max with dGTP (pmol/min)	K_m with dGTP (nM)
Enzyme	In vitro (μM)	Cell culture (nM)^a	V_max with dGTP (pmol/min)	K_m with dGTP (nM)
3MB	3.39 ± 0.18	96 ± 24	15.9	2.73
3MB/F160M/M184V	94.1 ± 9.7	1,136 ± 264	16.2	3.37
3MB/M184V	34.8 ± 0.73	451 ± 89	20.9	6.56
3MB/F160M	5.73 ± 0.26	Not done	20.6	2.73

Data from Yasutake et al. (38).