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Mature DCs programmed by CD8 T cells secrete proinflammatory factors. Shown are the levels of proinflammatory factors RANTES (A), IP-10 (B), IL-6 (C), and IL-12p70 (D) in DC culture with no treatment (DCNo treat), DC-CD8 coculture with NAE (DCNAE) or AE (DCAE), or maturation cocktail (DCCocktail) as determined by multiplex array. The Wilcoxon matched-pairs signed rank test was used to determine statistical significance.
