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. 2021 Jul;49(7):479–489. doi: 10.1124/dmd.121.000423

Fig. 1.

Fig. 1.

ENT1substrate pharmacophore correlation and fit (A) and mapping of gemcitabine (B), mizoribine (C), ribavirin (D), GS-9667 (E), and rabacfosfadine (F) to this pharmacophore. Purple features represent hydrogen bond donors, whereas gray features represent excluded volumes. Act, activity; Est, estimate; Err, error; HBD, hydrogen bond donor.