Table 1.
Metabolites | Day 7 | Day 21 | Day 35 | |||
---|---|---|---|---|---|---|
Trend | VIP | Trend | VIP | Trend | VIP | |
Myristic acid | +++ | 3.461 | ++ | 1.509 | ++ | 2.133 |
3,6-Octadienoylglycine | ++ | 2.105 | -- | 1.946 | ++ | 1.828 |
Uracil | ++ | 1.968 | / | 0.063 | + | 1.161 |
Mevalonic acid | + | 1.663 | / | 0.021 | / | 0.189 |
3-Hydroxybutyric acid | - | 1.078 | -- | 1.501 | -- | 1.943 |
Pantothenic acid | + | 0.824 | ++ | 1.409 | / | 0.528 |
1-Methyluric acid | - | 0.822 | / | 0.092 | ++ | 1.723 |
Epinephrine | + | 0.578 | + | 0.924 | / | 0.055 |
4-Hydroxyproline | / | 0.299 | + | 1.119 | + | 1.106 |
Succinic acid semialdehyde | / | 0.252 | - | 0.241 | - | 0.327 |
1-Methylhistidine | - | 0.213 | / | 0.004 | + | 1.148 |
Note: “-” represents metabolites with a downregulated trend, “+” represents metabolites with an upregulated trend, “--” and “++” represent significant difference from control at P < 0.05, and “---” and “+++” represent significant difference from control at P < 0.01.