Table 2.
Baseline characteristics of critically ill elderly patients with infection.
| Characteristic | All (n = 439) | Nonsurvivor (n = 132) | Survivor (n = 307) | p value |
|---|---|---|---|---|
| Age (years) (IQR) | 78 (73–83) | 79 (73–82.5) | 78 (73–83) | 0.996 |
| Gender, male, n (%) | 222 (50.6) | 71 (53.8) | 151 (49.2) | 0.376 |
|
| ||||
| Comorbidities, n (%) | ||||
| Diabetes mellitus | 176 (40.1) | 56 (42.4) | 120 (39.1) | 0.513 |
| Hypertension | 264 (60.1) | 81 (61.4) | 183 (59.6) | 0.731 |
| Chronic renal disease | 64 (14.6) | 19 (14.4) | 45 (14.7) | 0.943 |
| Cardiovascular disease | 54 (12.3) | 17 (12.9) | 37 (12.1) | 0.809 |
| Malignancy | 72 (16.4) | 39 (29.5) | 33 (10.7) | <0.001 |
|
| ||||
| Initial vital signs | ||||
| Systolic BP (mmHg) | 120.5 (98–141) | 114 (93.5–136.5) | 122 (98–146) | 0.036 |
| Diastolic BP (mmHg) | 70 (57–80) | 66 (54–80) | 70 (54.5–80) | 0.603 |
| Heart rate (beats/min) | 96 (80–112) | 96 (80–111) | 96 (84–118) | 0.578 |
| Respiratory rate (breaths/min) | 20 (20–24) | 20 (18–22) | 20 (20–24) | 0.067 |
| Body temperature (°C) | 36.8 (36.2–37.9) | 36.9 (36.2–37.9) | 36.8 (36.3–37.9) | 0.545 |
| KTAS level (1, 2), n (%) | 182 (41.5) | 56 (42.4) | 126 (40.0) | 0.788 |
|
| ||||
| Laboratory results, median (IQR) | ||||
| WBC count (109/L) | 11.6 (7.9–18.2) | 11.6 (7.6–18.4) | 11.5 (7.8–17.0) | 0.542 |
| Platelets | 207.0 (145.0–291.0) | 175.5 (113.0–263.5) | 214.0 (156.0–299.5) | 0.007 |
| Total bilirubin | 0.8 (0.5–1.3) | 1.0 (0.6–1.5) | 0.8 (0.5–1.2) | 0.022 |
| Albumin | 3.2 (2.7–3.6) | 3.0 (2.6–3.4) | 3.2 (2.7–3.6) | <0.001 |
| Lactate | 1.9 (1.2–3.4) | 2.3 (1.5–4.3) | 1.7 (1.2–2.8) | <0.001 |
| SOFA score | 6 (4–9) | 8 (5–11) | 5 (3–8) | <0.001 |
| Septic shock, n (%) | 123 (28.0) | 59 (44.7) | 64 (20.8) | <0.001 |
| Door-to-antibiotic time (min) | 188 (138–272) | 174 (131–261) | 194 (143–275) | 0.140 |
| Vasopressor at ED, n (%) | 184 (41.9) | 83 (62.9) | 101 (32.9) | <0.001 |
| Ventilator at ED, n (%) | 155 (35.3) | 66 (50.0) | 89 (29.0) | <0.001 |
| ED LOS (hours) | 8.0 (5.0–19.0) | 9.0 (5.1–28.4) | 8.0 (5.0–16.5) | 0.023 |
| ICU LOS (days) | 6.0 (3.0–12.0) | 7.5 (4.0–14.0) | 6.0 (3.0–12.0) | 0.050 |
| Hospital LOS (days) | 16.0 (9.0–28.0) | 13.5 (6.0–24.0) | 17.0 (10.0–29.0) | 0.002 |
BP: blood pressure; KTAS: Korean Triage and Acuity Scale; WBC: white blood cell; SOFA: Sequential Organ Failure Assessment; ED: emergency department; LOS: length of stay; ICU: intensive care unit.