Table 4.
Prognostic Accuracy of SOFA, qSOFA, and SIRS for 28-Day Mortality
| SOFA ≥2 | qSOFA ≥2 | SIRS ≥2 | |
|---|---|---|---|
| Sensitivity (95% CI) | 61.4 (53.3–69.0) | 19.6 (13.7–26.7) | 52.5 (44.4–60.5) |
| Specificity (95% CI) | 67.3 (65.1–69.4) | 92.4 (91.1–93.6) | 51.5 (49.2–53.7) |
| PPV (95% CI) | 13.6 (11.2–16.3) | 17.8 (12.4–24.3) | 8.3 (6.7–10.2) |
| NPV (95% CI) | 95.4 (94.2–96.5) | 93.2 (92.0–94.3) | 92.8 (91.1–94.3) |
| Likelihood ratio (+) | 1.9 (1.6–2.2) | 2.6 (1.8–3.7) | 1.1 (0.93–1.3) |
| Likelihood ratio (-) | 0.6 (0.5–0.7) | 0.9 (0.8–0.9) | 0.9 (0.8–1.1) |
| SOFA | qSOFA | SIRS | |
| AUROC (95% CI) | 0.68 (0.64–0.73) | 0.63 (0.58–0.67) | 0.52 (0.47–0.56) |
Abbreviations: AUROC, area under the receiver operating characteristic curve; CI, confidence interval; NPV, negative predictive value; PPV, positive predictive value.