Skip to main content
. 2021 Jun 5;34(4):947–954. doi: 10.1007/s10534-021-00320-1

Table 3.

Concentrations of different metals in heart, spleen, liver, cerebellum, and cortex of Fmr1 KO mice compared to WT controls

Metal Cortex Cerebellum Liver Spleen Heart
Na (µg/g) WT 1500 ± 97 1500 ± 360 790 ± 110 680 ± 220 1200 ± 230
Fmr1 KO 1500 ± 230 1900 ± 330 730 ± 73 590 ± 160 1400 ± 380
p 0.83 0.21 0.39 0.41 0.19
Mg (µg/g) WT 100 ± 13 120 ± 36 210 ± 19 160 ± 51 170 ± 48
Fmr1 KO 95 ± 18 140 ± 38 210 ± 31 150 ± 34 210 ± 48
p 0.61 0.4 0.8 0.51 0.16
P (µg/g) WT 2300 ± 280 3100 ± 980 3100 ± 240 3200 ± 1000 2100 ± 630
Fmr1 KO 2300 ± 420 3600 ± 1000 3000 ± 430 2900 ± 720 2500 ± 550
p 0.82 0.41 0.5 0.55 0.23
K (µg/g) WT 2400 ± 300 2500 ± 810 2900 ± 190 3200 ± 1000 2000 ± 640
Fmr1 KO 2300 ± 420 3100 ± 800 3100 ± 420 2900 ± 670 2700 ± 600
p 0.67 0.35 0.53 0.49 0.069
Mn (µg/g) WT 0.21 ± 0.014 0.33 ± 0.093 0.71 ± 0.05 0.15 ± 0.064 0.38 ± 0.083
Fmr1 KO 0.19 ± 0.039 0.36 ± 0.097 0.79 ± 0.13 0.16 ± 0.05 0.49 ± 0.15
p 0.39 0.69 0.14 0.69 0.11
Fe (µg/g) WT 6.6 ± 0.91 8.6 ± 2.6 70 ± 15 460 ± 200 43 ± 11
Fmr1 KO 7.6 ± 1.5 13 ± 2.8 66 ± 19 510 ± 190 62 ± 17
p 0.18 0.052 0.74 0.7 0.033 *
Cu (µg/g) WT 2.2 ± 0.27 3.2 ± 1.7 4.2 ± 0.93 0.64 ± 0.21 4.4 ± 1.2
Fmr1 KO 2 ± 0.44 4.4 ± 1.1 4.2 ± 1.2 0.55 ± 0.13 5.5 ± 1.4
p 0.39 0.31 0.96 0.44 0.16

*p < 0.05