Table 1.

List of proteins upregulated in hypoxia, IOX2, and VH032 treatment

Uniprot ID	Gene name	Hypoxia replicate 1	Hypoxia replicate 2	IOX2 replicate 1	IOX2 replicate 2	VH032 replicate 1	VH032 replicate 2
Q12983	BNIP3	18.11	3.33	11.59	2.6	8.33	2.03
P35318	ADML	6.47	4.73	2.05	4.81	1.47	3.44
O76061	STC2	3.24	1.59	1.58	4.36	1.84	1.31
P11169	GTR3	7.52	6.58	1.39	2.51	1.63	1.95
Q16790	CAH9	6.76	6.04	3.31	3.93	3.94	3.26
P06307	CCKN	1.43	2.46	1.71	1.8	1.35	1.98
Q16665	HIF1A	4	2.31	2.37	3.68	2.19	1.98
Q15413	RYR3	2.32	1.87	2.2	2.86	1.45	4.3
P98155	VLDLR	3.51	2.6	2.01	3.45	1.97	1.85
P05412	JUN	2.89	1.94	1.34	2.03	1.32	1.37
Q16877	F264	6.29	4.48	1.85	2.97	2.1	2.09
P11166	GTR1	3.59	2.79	1.35	1.72	1.47	1.42
Q9Y4K0	LOXL2	3.89	2.96	1.3	2.11	1.46	1.44
Q9BXL7	CAR11	2.13	1.72	1.85	2.33	1.56	3.23
Q9NX57	RAB20	2.5	1.93	1.44	2.34	1.58	1.49
P28300	LYOX	4.81	3.63	1.59	4.38	1.44	1.72
Q92597	NDRG1	5.06	4.25	1.36	1.58	1.62	1.41
B7ZBB8	PP13G	4.37	3.65	1.57	1.84	1.73	1.37
P13674	P4HA1	2.45	2.31	1.48	1.53	1.5	1.58
Q15118	PDK1	2.07	1.84	1.62	1.63	1.61	1.54
P09104	ENOG	3.03	2.62	1.39	2.23	1.7	1.74
Q9Y4C1	KDM3A	2.53	2.23	1.46	1.47	1.56	1.44
P27144	KAD4	1.42	1.38	1.31	1.38	1.33	1.37
O00469	PLOD2	2.76	2.53	1.41	1.5	1.55	1.58
Q9GZT9	EGLN1	1.87	1.61	1.37	1.44	1.39	1.34
Q9Y5U4	INSI2	2.19	2.18	1.31	2.39	1.32	1.54

Proteins were selected at a false discovery rate <0.01 and relative abundance to control DMSO >1.3 for each replicate. Uniprot ID and gene name are listed with relative abundance to DMSO control. In italics: transcripts of these proteins were found upregulated in hypoxia, IOX2, and VH032 by RNA-Seq (16).