Table I.

Clinical and histopathologic subtypes of Sweet syndrome

Classification	Findings
Clinical
Classic	Rapid development of painful, erythematous nodules and/or plaques
Giant cellulitis-like	Large erythematous vesicular, bullous, or hemorrhagic plaques
Necrotizing	Erythematous lesions with deep neutrophilic invasion and soft tissue necrosis
Pustular/bullous	Vesicles/pustules with or without coalescence into bullae
Histopathologic
Neutrophilic	Primary neutrophilic infiltrate within the dermis
Cryptococcoid	Degenerating inflammatory cells with resemblance to Cryptococcus capsule and acellular bodies resembling yeast
Histiocytoid	Primary mononuclear infiltrate in the dermis composed of MPO-positive histiocyte-like mononuclear cells
Lymphocytic	Primary lymphocytic infiltrate into dermis with immature granulocytes
Subcutaneous	Dense neutrophilic infiltrate within subcutis in lobular or septal patterns

MPO, Myeloperoxidase.