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. 2021 Jul 13;12:689663. doi: 10.3389/fimmu.2021.689663

Figure 1.

Figure 1

The biomarkers of endothelial activation and vascular integrity. (A) Plasma soluble Angiopoietin-2 concentration, (B) plasma soluble ICAM-1 concentration, and (C) plasma soluble VEGF concentration were significantly higher in adult corticosteroid resistant ITP patients (n = 88 compared with healthy volunteers n = 30). However, (D) plasma soluble Angiopoietin-1 concentration, (E) plasma soluble Fractalkine concentration, and (F) plasma soluble E-selectin concentration between adult corticosteroid resistant ITP patients and healthy volunteers show no markedly difference. Significance between these two groups was determined by Student’s t-test. Data are expressed as box-whisker plots: the central horizontal line, lower and upper of boxes depict the median, first quartile, and third quartile respectively; and the whisker extends to the minimal and maximal data point.