Table 4.
Logistic regression analysis evaluating predictors of no response to consecutive low-dose decitabine therapy for corticosteroid resistant ITP patients.
| OR | 95% CIr | P-value | ||
|---|---|---|---|---|
| Lower | Uppper | |||
| Univariable analysis of subject characteristics | ||||
| Age | 1.027 | 0.979 | 1.077 | 0.281 |
| Male | 2.000 | 0.446 | 8.963 | 0.365 |
| Baseline platelet | 0.947 | 0.860 | 1.043 | 0.272 |
| Angiopoietin-2 (50 ng/ml increase) | 1.084 | 0.991 | 1.186 | 0.078 |
| ICAM-1 (5 pg/ml increase) | 1.354 | 1.071 | 1.713 | 0.011 |
| Final multivariable prediction model | ||||
| ICAM-1 (5 pg/ml increase) | 1.368 | 1.060 | 1.764 | 0.016 |
| Angiopoietin-2 (50 ng/ml increase) | 1.082 | 0.947 | 1.235 | 0.247 |
Subject characteristics were chosen for the univariable analysis, and only two variables are shown in the final multivariable analysis. 95% CI indicates 95% confidence interval.