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. 2021 Jul 13;13:684171. doi: 10.3389/fnagi.2021.684171

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Copyright © 2021 Rehman, Tar, Olamide, Li, Kassubek, Böckers, Weishaupt, Ludolph, Wiesner and Roselli.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Tbk1 blockade enhances infiltration of the Stab Wound Injury (SWI) by peripheral immune cells. (A) In AMX-treated animals (at 7 dpi), the SWI site displayed a substantial increase in the density of CD45-bright cells including peripheral leukocytes; quantified in (B) and lymphocytes CD3⁺ cells; quantified in (C); average ± SD; two-way ANOVA with Tukey’s post hoc (n = 3 animals/group with 4 sections/animal. ^∗∗∗p < 0.001, ^****p < 0.0001; full statistical report in Supplementary Table 6). Upper panel, low magnification; insets at high magnification. Scale bars (both sets of panels) 200 μm.