Figure 1.

Protective effect of Ephx2 silencing on IECs. A – Photomicrographs of normal rat IEC-6 cells (magnification ×100 and ×200, respectively). After cell transfection, both the (B) protein expression and (C) mRNA expression of Ephx2 were significantly reduced.* p < 0.05, **p < 0.01 compared with NC group, n = 4. D – Cell viability was measured by CCK-8 assay in IEC-6 cells treated with H₂O₂ for 12, 24, and 48 h. *p < 0.05 compared with control group, ^{^}p < 0.05 compared with NC group, ^#p < 0.05 compared with NC + H₂O₂ group, n = 4