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. Author manuscript; available in PMC: 2021 Jul 27.
Published in final edited form as: J Med Chem. 2018 Sep 28;61(19):8875–8894. doi: 10.1021/acs.jmedchem.8b01108

Figure 7.

Figure 7.

RAS-GTP levels and corresponding pERK1/2T202/Y204 levels from HeLa cells that were treated for 10 min with up to 30 μM of compound 42, 64, 55, 60, or 61. EGF (50 ng/mL for 5 min) was used as a positive control for pathway stimulation. Data are representative of two independent experiments.