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. 2021 Jul 26;41(7):BSR20211280. doi: 10.1042/BSR20211280

Figure 2. Identification of DEGs between 48 normal and 372 CRC samples.

Figure 2

(A) Principal component analysis. (B) Volcano plot. Purple dots represent genes down-regulated in CRC; gray dots, genes not differing significantly between CRC and normal tissues; and red dots, genes up-regulated in CRC. (C) The volcano plot. Purple dots represent down-regulated genes, gray dots represent not significant genes, and red dots represent up-regulated genes. (D) GO analysis of functional enrichment of up-regulated genes. Dot size reflects the number of genes enriched under the given ontology term, and the color indicates the significance of enrichment.