Table 5.
Odds ratios (ORs) for cognitive decline according to the exposure combination
| Fatty acid | ||||||
|---|---|---|---|---|---|---|
| Exposure combination | LCPUFA | DHA | EPA | ARA | ||
| ORs (95% CIs) | ||||||
| Crude Model | ||||||
| Fatty acid intake (L) | x | Art appreciation (L) | 1 (Reference) | 1 (Reference) | 1 (Reference) | 1 (Reference) |
| Fatty acid intake (L) | x | Art appreciation (H) | 1.03 (0.58–1.85) | 0.98 (0.55–1.75) | 0.93 (0.51–1.69) | 1.01 (0.57–1.80) |
| Fatty acid intake (H) | x | Art appreciation (L) | 1.01 (0.64–1.58) | 1.09 (0.69–1.71) | 1.06 (0.68–1.67) | 0.96 (0.61–1.51) |
| Fatty acid intake (H) | x | Art appreciation (H) | 0.29 (0.14–0.60) | 0.32 (0.15–0.67) | 0.37 (0.18–0.73) | 0.26 (0.12–0.56) |
| Model I | ||||||
| Fatty acid intake (L) | x | Art appreciation (L) | 1 (Reference) | 1 (Reference) | 1 (Reference) | 1 (Reference) |
| Fatty acid intake (L) | x | Art appreciation (H) | 1.00 (0.55–1.82) | 0.97 (0.54–1.75) | 0.91 (0.50–1.67) | 0.98 (0.54–1.76) |
| Fatty acid intake (H) | x | Art appreciation (L) | 0.99 (0.62–1.57) | 1.09 (0.69–1.74) | 1.04 (0.66–1.66) | 0.95 (0.60–1.51) |
| Fatty acid intake (H) | x | Art appreciation (H) | 0.30 (0.15–0.63) | 0.34 (0.16–0.71) | 0.38 (0.19–0.76) | 0.28 (0.13–0.60) |
| Model II | ||||||
| Fatty acid intake (L) | x | Art appreciation (L) | 1 (Reference) | 1 (Reference) | 1 (Reference) | 1 (Reference) |
| Fatty acid intake (L) | x | Art appreciation (H) | 0. 94 (0.47–1.86) | 0.96 (0.48–1.90) | 0.80 (0.40–1.60) | 0.95 (0.49–1.85) |
| Fatty acid intake (H) | x | Art appreciation (L) | 0.84 (0.49–1.42) | 1.01 (0.59–1.71) | 0.89 (0.53–1.51) | 0.94 (0.55–1.60) |
| Fatty acid intake (H) | x | Art appreciation (H) | 0.25 (0.11–0.56) | 0.29 (0.13–0.65) | 0.33 (0.15–0.72) | 0.25 (0.10–0.59) |
Note: Multiple logistic analysis
Model I: Adjusted for sex and age
Model II: Adjusted for sex and age; MMSE score; BMI; education level; marital status; smoking status; alcohol consumption; energy intake; physical activity; employment status; depressive tendency; and history of hypertension, hyperlipidemia, ischemic heart disease stroke and diabetes
Fatty acid intake was divided into two groups (high,low) based on the median values according to sex. Art appreciation was divided into two groups based on the frequency of participation: “at least once or more per month” (high); “once or several times per year or less” (low)
ARA, arachidonic acid; CI, confidence interval; DHA, docosahexaenoic acid; EPA, eicosapentaenoic acid; L, low; LCPUFAs, long-chain polyunsaturated fatty acids; H, high; OR, odds ratio