Table 2.

Association between lagged monthly duration of CPAP use and risk of new CV events among Medicare beneficiaries with OSA, stratified by time since first CPAP fill.

Lagged Monthly Duration of CPAP Use	25-Month Outcome (407 events)	12-Month Outcome (246 events)	6-Month Outcome (138 events)	3-Month Outcome (99 events)
Unadjusted	0.98 (0.96–0.99)	0.95 (0.92–0.99)	0.84 (0.77–0.93)	0.90 (0.75–1.08)
Adjusted*	0.98 (0.97–1.00)**	0.96 (0.92–0.99)	0.85 (0.77–0.93)	0.91 (0.76–1.09)

Values are presented as unadjusted and adjusted HRs (95% CI). *25-month outcome model adjusted for cataracts, congestive heart failure, chronic kidney disease, hypertension; 12-month outcome model adjusted for age, congestive heart failure, chronic kidney disease; 6-month outcome model adjusted for age, congestive heart failure; 3-month outcome model adjusted for age, atrial fibrillation, chronic kidney disease. **P = .02. CI = confidence interval, CPAP = continuous positive airway pressure, CV = cerebrovascular, HR = hazard ratio, OSA = obstructive sleep apnea.