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. 2021 Jul 22;17:2429–2439. doi: 10.2147/NDT.S320374

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© 2021 Sirivarasai et al.

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Proposed interaction among mercury, homocysteine, and network proteins related to cognitive impairment. Stronger associations are represented by thicker lines. Protein-protein interactions are shown in grey, chemical-protein interactions are shown in green, and interactions between chemicals are shown in red.

Abbreviations: BHMT, betaine-homocysteine S-methyltransferase; CAT, catalase; GPX, glutathione peroxidase; GSR, glutathione reductase; Hydrogen perox, hydrogen peroxide; MeHg, methylmercury; MT1A, metallothionein 1A; MTR, 5-methyltetrahydrofolate-homocysteine methyltransferase; Reduced glutat; reduced glutathione; SOD, superoxide dismutase; Zn, zinc.