Table 3.
Logistic Regression Analysis of Cognitive Impairment
| OR (95% CI) | P value | Adjusted ORa (95% CI) | P value | ||
|---|---|---|---|---|---|
| Age (y) | 45–55 | Reference | Reference | ||
| 56–65 | 1.82 (1.05–3.14) | 0.031 | 1.36 (1.09–2.07) | 0.038 | |
| Blood mercury (µg/L)b | Tertile 1 | Reference | Reference | ||
| Tertile 2/3 | 2.07 (1.31–3.74) | 0.003 | 1.89 (1.18–3.09) | 0.014 | |
| MTIA rs8052394 | AA | Reference | Reference | ||
| AG/GG | 1.61 (1.08–3.04) | 0.023 | 1.76 (1.24–2.96) | 0.017 | |
| Blood mercury (µg/L)b | MTIA rs8052394 | ||||
| Tertile 1 | AA | Reference | Reference | ||
| Tertile 1 | AG/GG | 0.74 (0.42–1.39) | 0.064 | 1.08 (0.86–1.29) | 0.121 |
| Blood mercury (µg/L)b | MTIA rs8052394 | ||||
| Tertile 3 | AA | Reference | Reference | ||
| Tertile 3 | AG/GG | 1.88 (1.13–3.04) | 0.042 | 2.34 (1.30–3.67) | 0.034 |
Notes: aAdjusted OR calculated from the logistic regression adjusted for sex, education level, BMI and MS components, b Geometric mean of the blood mercury level as a tertile value.
Abbreviations: OR, odds ratio; CI, confidence interval.