Expression of SIRT1 in human kidney tissues. a Representative images of SIRT1 expression by immunohistochemistry in renal biopsy specimen diagnosed with MN, MCD, and FSGS. b IOD analysis of SIRT1 immunohistochemistry. Results are presented as means ± SEM (n = 6). *p < 0.05 versus normal. SIRT1, silent mating type information regulation 2 homolog 1; MN, membrane nephropathy; MCD, minimal change disease; FSGS, focal segmental glomerulosclerosis.