Table 3.
Survival results (overall survival, disease-free survival, metastasis-free survival and breast cancer-specific survival): Cox model adjusted on significant univariate criteria for all patients and for patients with tumor subtypes known, according to pN status [pN0, pN0(i+), pN1mi, pN1macro]
| All patients | All patients |
||
|---|---|---|---|
| HR | P value | 95% CI | |
| Overall survival | |||
| Positive ER | |||
| pN0 | 1 | ||
| pN0(i+) | 0.872 | 0.595 | 0.527-1.444 |
| pN1mi | 0.930 | 0.665 | 0.670-1.292 |
| pN1a | 1.828 | <0.0001 | 1.368-2.442 |
| Subtypes | |||
| pN0 | 1 | ||
| pN0(i+) | 1.089 | 0.788 | 0.585-2.026 |
| pN1mi | 0.999 | 0.994 | 0.674-1.479 |
| pN1a | 1.973 | <0.0001 | 1.391-2.798 |
| Disease-free survival | |||
| Positive ER | |||
| pN0 | 1 | ||
| pN0(i+) | 1.102 | 0.524 | 0.817-1.487 |
| pN1mi | 0.936 | 0.551 | 0.751-1.165 |
| pN1a | 1.408 | 0.001 | 1.148-1.726 |
| Subtypes | |||
| pN0 | 1 | ||
| pN0(i+) | 1.328 | 0.133 | 0.918-1.921 |
| pN1mi | 0.960 | 0.759 | 0.739-1.246 |
| pN1a | 1.505 | 0.001 | 1.178-1.921 |
| Metastasis-free survival | |||
| Positive ER | |||
| pN0 | 1 | ||
| pN0(i+) | 0.728 | 0.250 | 0.423-1.251 |
| pN1mi | 0.851 | 0.371 | 0.598-1.212 |
| pN1a | 1.443 | 0.016 | 1.071-1.943 |
| Subtypes | |||
| pN0 | 1 | ||
| pN0(i+) | 0.847 | 0.635 | 0.426-1.685 |
| pN1mi | 0.905 | 0.633 | 0.601-1.363 |
| pN1a | 1.509 | 0.021 | 1.064-2.140 |
| Breast-cancer-specific survival | |||
| Positive ER | |||
| pN0 | 1 | ||
| pN0(i+) | 0.848 | 0.663 | 0.404-1.779 |
| pN1mi | 1.122 | 0.372 | 0.787-1.897 |
| pN1a | 1.960 | 0.001 | 1.328-2.893 |
| Subtypes | |||
| pN0 | 1 | ||
| pN0(i+) | 0.893 | 0.829 | 0.321-2.489 |
| pN1mi | 1.355 | 0.255 | 0.803-2.288 |
| pN1a | 2.216 | 0.001 | 1.382-3.554 |
Significant values are indicated in bold.