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. 2021 Jul 27;25:100675. doi: 10.1016/j.imu.2021.100675

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© 2021 The Authors

Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.

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Fig. 10 — Gibbs free energy landscape. The scale shows the free energy values. Blue and green regions are more stable than red and yellow. MT S68F shows more stability than WT based on the free energy landscape. WT exhibited more stability than P71S and L73F. (For interpretation of the references to color in this figure legend, the reader is referred to the Web version of this article.)