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. 2021 May 1;203(9):1173–1182. doi: 10.1164/rccm.202005-1808OC

Table 3.

Estimated Differences in Hypopnea and Apnea Duration (in Seconds) per SD Change in Physiologic Traits

Characteristic NREM Hypopnea Duration
NREM Obstructive Apnea Duration
Model 1
Model 2
Model 3
Model 1
Model 2
Model 3
β (SE) β (SE) β (SE) β (SE) β (SE) β (SE)
Loop gain (sensitivity) −1.04 (0.13)* −0.80 (0.12)* −0.27 (0.11) −0.61 (0.21)* −0.38 (0.19) −0.36 (0.20)
Arousal threshold (%eupnea) 1.97 (0.14)* 1.48 (0.13)* 1.39 (0.15)* 2.37 (0.22)* 1.91 (0.21)* 1.92 (0.25)*
Circulatory delay, s 2.81 (0.13)* 2.17 (0.13)* 2.53 (0.13)* 3.04 (0.21)* 2.28 (0.22)* 3.10 (0.21)*
Collapsibility per Vpassive (%eupnea) −1.89 (0.16) −1.43 (0.14)* −0.71 (0.16)* −2.16 (0.23)* −1.72 (0.22)* −0.95 (0.25)*

Definition of abbreviation: NREM = non-REM.

Model 1: unadjusted. Model 2: adjusted for age, sex, BMI, race, and smoking status. Model 3: adjusted for other three physiologic traits.

*

P < 0.01.

P < 0.05.

Higher Vpassive indicates less-severe collapsibility; thus, longer events are associated with more severe collapsibility.