Table 4.
Multivariate Linear Regression of the Associations between NREM Hypopnea Duration and Sample Characteristics
| Model 1 [β (SE)] | + Loop Gain [β (SE)] | + Arousal Threshold [β (SE)] | + Circulatory Delay [β (SE)] | + Collapsibility [β (SE)] | + All Physiologic Traits [β (SE)] | |
|---|---|---|---|---|---|---|
| Intercept | 20.62 (0.24) | 20.45 (0.23) | 21.08 (0.23) | 20.80 (0.22) | 21.08 (0.23) | 21.19 (0.20) |
| Age, yr | 0.65 (0.13)* | 0.71 (0.13)* | 0.61 (0.12)* | 0.40 (0.12)* | 0.53 (0.13)* | 0.41 (0.11)* |
| Sex | ||||||
| M | 2.38 (0.25)* | 2.56 (0.25)* | 1.57 (0.25)* | 1.91 (0.23)* | 1.60 (0.25)* | 0.99 (0.21)* |
| F | REF | REF | REF | REF | REF | REF |
| Race | ||||||
| Non-Hispanic white | REF | REF | REF | REF | REF | REF |
| Asian | 1.34 (0.46)* | 1.43 (0.45)* | 0.80 (0.44)† | 1.20 (0.42)* | 0.73 (0.44)† | 0.49 (0.38) |
| Black | −0.79 (0.31)‡ | −0.52 (0.31)† | −0.81 (0.29)* | −0.43 (0.28) | −0.71 (0.30)‡ | −0.04 (0.26) |
| Hispanic | 0.14 (0.33) | 0.13 (0.32) | 0.07 (0.31) | 0.01 (0.29) | 0.02 (0.31) | −0.02 (0.26) |
| BMI, kg/m2 | −1.18 (0.13)* | −1.00 (0.13)* | −1.19 (0.12)* | −0.46 (0.12)* | −1.30 (0.12)* | −0.50 (0.11)* |
Definition of abbreviations: BMI = body mass index; NREM = non-REM; REF = reference.
Weighted least-squares regression analysis, with weights taken to be the inverse of the squared outcome, estimating observation-specific variance. Model 1: age, sex, BMI, race, and smoking status. Model 2: model 1 + loop gain. Model 3: model 1 + arousal threshold. Model 4: model 1 + circulatory delay. Model 5: model 1 + collapsibility (per Vpassive; lower values represent greater collapsibility). Model 6: model 1 + loop gain, arousal threshold, circulatory delay, passive collapsibility threshold. n = 1,532 in all models.
*
P < 0.01.
†
P < 0.10.
‡
P < 0.05.