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. Author manuscript; available in PMC: 2021 Jul 27.
Published in final edited form as: Inorganics (Basel). 2019 Aug 18;7(8):101. doi: 10.3390/inorganics7080101

Table 2.

ADI1 and ADI1GP dependences of cancer cell lines.

Types of Cancer Tissue/ Cell
type		 ADI1GP expression Metastatic/
apoptotic		 Mechanism
Hepatocellular carcinoma Tissue , J7 and Huh7 Down regulated by CAV1, overexpressed No information Not proposed
Prostate cancer[22, 31] Tissue, LNCaP and PC3 Observed in epithelial cells, little/no expression in stromal cells.
Expression may be Mib regulated, Gleason gr. 3 prostate tumor tissue < ADI1GP than benign tissue.		 Apoptotic Associated with metal binding
Pancreatic ductal adenocarcinoma[42] DanG, BxPC3, and Panc-1 Overexpressed Metastatic ADI1GP MT1-MMP interaction