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. 2021 Jun 22;17(10):2633–2651. doi: 10.7150/ijbs.58514

Figure 5.

Figure 5

YTHDC2 overexpression suppresses H1299 cells growth in vivo. (A) Images of the xenograft tumors formed in nude mice injected with YTHDC2-overexpressing and control cells. (B) Volume and (C) weight of xenograft tumors isolated from nude mice. (D) Representative images and (E) quantification of the results of cell cycle analysis of single cell suspensions yielded from xenograft tumors. (F) Representative images of hematoxylin and eosin staining, and immunohistochemical staining of YTHDC2, Ki-67, cyclin D1, E-cadherin and N-cadherin in xenograft tumors derived from nude mice. Scale bar, 50 µm; **P<0.01 vs. blank group. YTHDC2, YTH domain containing 2.